Quick start with MestReNova NMR processing software

This software will run under Windows, Mac OS X, and various versions of Linux (with installers specific to the Linux release).   You can download the appropriate full version of the program for your computer from 
Choose the highest numbered (most recent) release version and save the downloaded file to your computer.  This is a self extracting installation program.  Download the manual at the same time!

Note that the MestReNova Lite program distributed with ChemDraw is licensed separately and WON'T work with our license file. If you have installed the Lite version, uninstall it, and install the full version.

You will need a license file, which we will email you on request.  Save this license file to your computer also.  Run the self extracting installer, and when prompted, browse to the location where you saved the license file. You need to do this while you are on the Caltech network, either with a hard-wired connection or on the secure wireless network. The licensing step won't work if you are on an external network, but once you have checked out a license, you can use the software on any network for the next 90 days. After that, you will need to be on the Caltech network again to renew your license in order for the program to keep working. We have a unlimited count license for the NMR processing features, and a limited count license for chemical shift prediction; we don't license the other features, such as mass spec processing.  The first time you run the program, you will get error messages about these missing license features. Just check the boxes including the one saying "I've read this information," exit and restart the program, and the messages won't reappear. You can use the version of the program you start with indefinitely. However, it is recommended to update your MNova periodically, which requires a current site license file (we get a new one annually).

You can get your data on your computer through shared network drives, secure ftp, or USB sticks--see the web page on retrieving your data.

When you open a Varian data file in MestReNova, in most cases you will not need to do any explicit processing of the 1D spectrum--the processing parameters used in VnmrJ will be copied and applied automatically.  You have the option to apply different types of apodization to the spectrum, for example to do resolution enhancement, if you wish.  The auto-process feature works for both 1D and 2D spectra, although for 2D, there are a number of useful processing tricks to make cosmetic improvements to the data.  Opening multiple spectra will start a PowerPoint-like column of thumbnail images of the spectra you have open.  As with PowerPoint, if you save this file, you save all the slides.  You can export directly to PDF format and choose to save one, multiple, or all spectra open in MestReNova to the PDF file. 

Here is a Power Point introduction to MestReNova processing features from Chen Peng at Mestrelabs: MNova.pptx

Dave 05/20/19